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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Carlos García | 217 | 2003-2013 | |
| 2 | Mike Reilly | 209 | 2012-2019 | |
| 3 | Jorge Cantú | 185 | 2001-2013 | |
| 4 | Ángel López | 178 | 1973-1988 | |
| 5 | José Vásquez | 173 | 1996-2003 | |
| 6 | Miguel Germán# | 170 | 2006-2022 | |
| 7 | Kevin Hannah | 169 | 1997-2007 | |
| 8 | Bobby Morrison | 161 | 2005-2014 | |
| 9 | David Everhart | 157 | 2011-2019 | |
| 10 | Toshinobu Ohayashi | 152 | 2001-2015 | |
| 11 | Alan Holley | 148 | 2012-2020 | |
| 12 | Alejandro González | 147 | 2002-2010 | |
| 13 | Aaron Nelson | 146 | 1995-2001 | |
| 13 | James Wilson | 146 | 1996-2002 | |
| 15 | Gilbert Palmer | 141 | 2010-2015 | |
| 16 | Chris Flanagan | 138 | 2015-2020 | |
| 16 | Jason Watson | 138 | 2014-2021 | |
| 18 | William Parker | 137 | 2002-2012 | |
| 19 | Jorge Morales | 132 | 1991-1999 | |
| 20 | Stephen Dannatt | 131 | 1998-2006 | |
| 21 | Luis Caro | 130 | 1988-1997 | |
| 22 | Ángel Amaya# | 129 | 2016-2023 | |
| 22 | John Armstrong# | 129 | 2010-2016 | |
| 22 | Chris Edwards | 129 | 2009-2014 | |
| 25 | Ron Davis | 128 | 1982-1987 | |
| 25 | Luke Wallace | 128 | 2012-2018 | |
| 27 | Eric Callwood | 127 | 2005-2019 | |
| 28 | Silas Phipps | 126 | 1981-1990 | |
| 29 | Juan Gonzáles | 123 | 2010-2016 | |
| 29 | Jesús Reyes | 123 | 2005-2015 | |
| 31 | Luis Villegas | 122 | 2011-2021 | |
| 32 | Jim Martin | 121 | 1995-1999 | |
| 32 | Eduardo Rúbio# | 121 | 2011-2020 | |
| 34 | José Gómez | 120 | 2010-2016 | |
| 34 | Adam Peterson | 120 | 2004-2011 | |
| 36 | Bill Connor | 119 | 1999-2008 | |
| 37 | Scott Sanderson | 118 | 2008-2012 | |
| 38 | Jody Hall | 117 | 1984-1996 | |
| 38 | Kenneth Jensen | 117 | 2002-2014 | |
| 40 | Santiago Camacho | 116 | 1988-1996 | |
| 41 | Dennis Miller | 115 | 2007-2017 | |
| 41 | Wilbert Robinson | 115 | 2003-2013 | |
| 41 | David Witt | 115 | 1970-1976 | |
| 44 | Enrique Díaz | 114 | 2011-2017 | |
| 45 | Ramón Gutiérrez | 113 | 2000-2009 | |
| 45 | Craig Mullen | 113 | 1997-2003 | |
| 47 | Alberto Ramos | 112 | 1996-2000 | |
| 48 | Félix Pineda | 111 | 2004-2014 | |
| 49 | Sergio Medina | 110 | 1997-2003 | |
| 50 | Adam Fowler | 109 | 1995-2000 | |
| 50 | David Thomas | 109 | 1976-1984 | |
| 52 | John Davidson | 108 | 2008-2016 | |
| 52 | Jesús Esparza | 108 | 2007-2013 | |
| 54 | Felipe Hernández | 106 | 1973-1986 | |
| 54 | Sean Russell | 106 | 2007-2013 | |
| 56 | Lindsay Armstrong | 105 | 2001-2009 | |
| 56 | Jeff Cook | 105 | 2009-2015 | |
| 56 | Lorne Curry# | 105 | 2008-2019 | |
| 56 | Mike James | 105 | 2012-2018 | |
| 56 | Javier Serrano | 105 | 2015-2019 | |
| 61 | Alonso Castillo | 104 | 1995-2001 | |
| 61 | Bob Waller | 104 | 1999-2009 | |
| 63 | Juan Ortega | 103 | 2008-2012 | |
| 63 | Eric Powell | 103 | 2010-2016 | |
| 63 | Alfredo Rodríguez | 103 | 1977-1993 | |
| 66 | Ron Curry | 102 | 2001-2009 | |
| 66 | Nathaniel Thompson | 102 | 1999-2006 | |
| 66 | Justin Williams# | 102 | 2014-2019 | |
| 69 | David Baker | 101 | 1970-1980 | |
| 69 | William Parsons | 101 | 1973-1980 | |
| 71 | Buddy Morgan | 100 | 2001-2009 | |
| 71 | Mauro Rodríguez | 100 | 1992-2004 | |
| 71 | Mark Sutton | 100 | 2008-2010 | |
| 74 | Nathan Clark | 98 | 1991-1998 | |
| 74 | Luke Jordan | 98 | 1999-2006 | |
| 74 | Virgil Tucker | 98 | 2011-2017 | |
| 77 | Manuel Baca | 97 | 2003-2013 | |
| 77 | Carlos Bamentos | 97 | 1994-1999 | |
| 77 | Mark McRudds | 97 | 1976-1983 | |
| 77 | Blake Zimmerman | 97 | 2003-2008 | |
| 81 | Alfredo Benavides | 95 | 1971-1980 | |
| 81 | Héctor Chávez | 95 | 1979-1985 | |
| 81 | George Glendenning | 95 | 1991-1996 | |
| 81 | Jason Henderson | 95 | 2011-2019 | |
| 81 | Mike Howard | 95 | 2007-2011 | |
| 81 | Dale Marsh | 95 | 2003-2014 | |
| 81 | Roger Murphy | 95 | 2006-2015 | |
| 88 | Felipe Brito | 94 | 2001-2012 | |
| 88 | Jeffrey Frank | 94 | 1971-1976 | |
| 88 | Harvey Horton | 94 | 2003-2007 | |
| 88 | Pete Hoskins | 94 | 1979-1984 | |
| 88 | Aaron Lyon | 94 | 2007-2015 | |
| 88 | Luis Marín | 94 | 1998-2003 | |
| 88 | Frederick Rogers | 94 | 2004-2014 | |
| 95 | Randy Bennett | 93 | 2014-2020 | |
| 95 | Brent Morris | 93 | 1972-1981 | |
| 97 | Tommy Allen | 92 | 1982-1988 | |
| 97 | Frank Martin | 92 | 2010-2015 | |
| 97 | Tim Meadows | 92 | 2008-2014 | |
| 97 | Jorge Pacheco | 92 | 2007-2015 |
