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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Roderick Mosley* | 384 | 1995-2011 | |
| 2 | Desmond Irvin# | 324 | 2003-2023 | |
| 3 | Paul Oglethorpe# | 310 | 2010-2023 | |
| 4 | Weldon Harrell | 305 | 1997-2010 | |
| 5 | Joe Warren* | 276 | 1983-1996 | |
| 6 | Miguel López* | 265 | 1997-2016 | |
| 7 | Michael Long | 248 | 1981-1994 | |
| 8 | Harry Allen | 236 | 1997-2016 | |
| 9 | Sherman Roberts# | 202 | 2009-2023 | |
| 10 | Miguel Barrera | 195 | 2002-2019 | |
| 11 | Mario Rodríguez | 184 | 1974-1991 | |
| 12 | Zachary Millett | 179 | 1978-1989 | |
| 13 | Eddie Anderson | 174 | 2008-2016 | |
| 14 | Kyle Moon | 165 | 2000-2014 | |
| 15 | Hiang-ta Siew | 157 | 1981-1994 | |
| 16 | James Combs | 156 | 1997-2009 | |
| 16 | Ty Johnston | 156 | 2007-2015 | |
| 18 | Giampaolo Cadalora | 139 | 2002-2012 | |
| 18 | William West | 139 | 2013-2021 | |
| 20 | Artie Bicknell* | 137 | 1991-2003 | |
| 20 | Cory Cotton | 137 | 2001-2013 | |
| 22 | Nelson English# | 135 | 2013-2023 | |
| 23 | Jesse Wood# | 132 | 2017-2023 | |
| 24 | Mario Rivera# | 131 | 2016-2023 | |
| 25 | Fred Andrews | 129 | 1977-1994 | |
| 25 | Glenn Rogers | 129 | 2018-2022 | |
| 27 | Freddie Fleming | 128 | 1986-1997 | |
| 28 | Vincente Frías | 127 | 1970-1979 | |
| 29 | Kel Harris | 119 | 1977-1991 | |
| 30 | Arthur Gore | 117 | 1996-2004 | |
| 30 | Bob MacGruder | 117 | 2001-2011 | |
| 32 | Daniel Pope# | 116 | 2013-2023 | |
| 32 | Michael Stark | 116 | 1996-2003 | |
| 34 | Andy Green | 114 | 2000-2009 | |
| 34 | Chris Murphy | 114 | 2001-2010 | |
| 36 | Steve Houston# | 113 | 2015-2023 | |
| 36 | Kelsey Wood | 113 | 2003-2012 | |
| 38 | Carl Morgan | 112 | 1990-2000 | |
| 39 | Cecil Jacobs | 111 | 2007-2020 | |
| 40 | Vince Collins | 108 | 1996-2010 | |
| 40 | Jesús Reyes | 108 | 1986-2000 | |
| 42 | Frank Gary# | 107 | 2013-2023 | |
| 42 | Adrian McFarland# | 107 | 2008-2022 | |
| 44 | Roberto Ferreira | 106 | 1970-1978 | |
| 44 | Toshiki Nishimura# | 106 | 2017-2023 | |
| 46 | Billy McDonald# | 101 | 2009-2023 | |
| 46 | Salvador Ramírez | 101 | 1982-1992 | |
| 48 | Randall Helmick | 99 | 1986-1997 | |
| 49 | Juan Rodríguez | 98 | 1970-1979 | |
| 50 | Bob Holmes | 97 | 1977-1988 | |
| 51 | Bill Knapp | 95 | 2003-2019 | |
| 51 | Rintaro Oyama | 95 | 1995-2003 | |
| 53 | Chad Church | 94 | 1989-1998 | |
| 53 | Luis Contreras | 94 | 1970-1979 | |
| 55 | Jeffery Becker | 93 | 1996-2008 | |
| 55 | Chris Haines | 93 | 2013-2022 | |
| 55 | Jim Miller | 93 | 1986-1996 | |
| 58 | Artie Ervin | 92 | 2004-2009 | |
| 58 | Oliver Ferrer | 92 | 2010-2018 | |
| 58 | Jeff Osborne# | 92 | 2018-2023 | |
| 61 | Bob Morgan | 91 | 2000-2017 | |
| 61 | Ryan Pope# | 91 | 2008-2023 | |
| 63 | Jared O'Quinn | 89 | 1979-1985 | |
| 63 | Dennis Porter | 89 | 1970-1979 | |
| 63 | Manuel Ybarra | 89 | 2001-2011 | |
| 66 | Marcos Valdéz | 88 | 1970-1976 | |
| 66 | Clinton Watkins | 88 | 1975-1989 | |
| 68 | Cipriano Ramírez | 87 | 1997-2003 | |
| 68 | Mark White | 87 | 2000-2010 | |
| 70 | David Mack | 86 | 1983-1989 | |
| 71 | Jonathan Jones | 85 | 1980-1993 | |
| 72 | Pedro López* | 83 | 1974-1991 | |
| 73 | Víctor Cordero | 82 | 2012-2020 | |
| 73 | Mark Merritt# | 82 | 2018-2023 | |
| 73 | Cedric Peters | 82 | 1974-1983 | |
| 76 | Roy Green | 81 | 1970-1975 | |
| 76 | Michael Hargrove | 81 | 2014-2021 | |
| 76 | José Pagán | 81 | 1995-2009 | |
| 76 | Yoshino Sugimoto | 81 | 1970-1983 | |
| 80 | Bartolo Aguilar | 79 | 2002-2015 | |
| 80 | Juan Velázquez | 79 | 1992-1999 | |
| 82 | Luis López# | 78 | 2017-2023 | |
| 82 | Bobby Reynolds | 78 | 1996-2007 | |
| 84 | Kenneth Brown | 76 | 1992-2000 | |
| 85 | Jason Callahan | 75 | 1986-1997 | |
| 85 | Steve Estes | 75 | 1998-2007 | |
| 87 | Tony Marino | 74 | 1993-2001 | |
| 87 | Edward Rice | 74 | 1970-1973 | |
| 87 | Luis Rodríguez | 74 | 1981-1987 | |
| 90 | Jorge Freitas | 73 | 2011-2018 | |
| 90 | Albert Torrez | 73 | 2002-2017 | |
| 92 | Will Brooks | 72 | 1994-1999 | |
| 92 | Ron Leach | 72 | 1985-1991 | |
| 92 | José Morales | 72 | 2012-2021 | |
| 95 | Landon Brown | 71 | 1973-1983 | |
| 95 | Héctor Campos | 71 | 1998-2008 | |
| 95 | Gordon Lowe# | 71 | 2015-2023 | |
| 95 | Matt Wilkins | 71 | 2007-2019 | |
| 99 | Daniel Chase | 70 | 1980-1987 | |
| 99 | Orlando González | 70 | 1993-2005 |
