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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | António Yan | 128 | 2012-2016 | |
| 2 | Matt Hughes# | 116 | 2017-2021 | |
| 3 | Marvin Wheeler | 111 | 2013-2017 | |
| 4 | Luis Torres | 103 | 2001-2004 | |
| 5 | Francisco Arredondo | 100 | 1996-2006 | |
| 6 | Donovan Adams | 99 | 2003-2006 | |
| 7 | Cale Patterson | 86 | 2007-2014 | |
| 8 | José Torres | 84 | 1975-1984 | |
| 9 | David Kerr | 79 | 2007-2012 | |
| 10 | Bill Garrett | 78 | 1995-1999 | |
| 11 | Alberto Ruíz | 76 | 2003-2009 | |
| 11 | Jim Wilkerson | 76 | 1979-1988 | |
| 13 | Denver Butler | 73 | 2015-2020 | |
| 13 | Jesús González | 73 | 1999-2001 | |
| 15 | Juan Valle | 70 | 2012-2014 | |
| 16 | Luis Montero | 69 | 1998-2008 | |
| 16 | Theron Simon | 69 | 2003-2009 | |
| 18 | Luis Soto | 67 | 2010-2013 | |
| 19 | Tommy Beasley | 66 | 2000-2004 | |
| 19 | Logan Harris | 66 | 2014-2019 | |
| 19 | Raúl Hernández | 66 | 2006-2012 | |
| 19 | Joseph Stewart | 66 | 2003-2009 | |
| 23 | Harry Bannatyne | 65 | 2004-2010 | |
| 23 | Jeremy Dundee | 65 | 2001-2010 | |
| 23 | Ramón Vargas | 65 | 2006-2010 | |
| 26 | Gerardo Sánchez | 64 | 1998-2002 | |
| 26 | Miguel Angel Zamora | 64 | 1986-1996 | |
| 28 | Joe Herman# | 63 | 2015-2023 | |
| 28 | Miguel Zúńiga | 63 | 1977-1985 | |
| 30 | Roberto Pérez | 62 | 1984-1988 | |
| 31 | Sean Carver | 61 | 2005-2008 | |
| 31 | José García | 61 | 2005-2008 | |
| 33 | Ken Anaya# | 60 | 2017-2023 | |
| 33 | Jesús Galindo | 60 | 2009-2017 | |
| 35 | Dennis Kerr | 59 | 2007-2015 | |
| 35 | Todd Merritt | 59 | 2009-2013 | |
| 37 | Ken Bennett | 58 | 2010-2015 | |
| 37 | Jeremy Dillard | 58 | 1974-1981 | |
| 39 | José Cardenas | 57 | 2006-2010 | |
| 39 | Miguel Castaneda | 57 | 2015-2021 | |
| 39 | Karl Coleman | 57 | 1979-1983 | |
| 39 | Chris Conway | 57 | 1997-1999 | |
| 39 | Pancho Soto | 57 | 1979-1984 | |
| 39 | Jason Sparks | 57 | 2009-2013 | |
| 45 | Christian Cook | 56 | 1994-2000 | |
| 45 | Dennis DeWitt | 56 | 1976-1981 | |
| 45 | Phillip Swanson | 56 | 1979-1982 | |
| 48 | Pedro Flores | 55 | 2007-2014 | |
| 48 | Chris McKinney# | 55 | 2019-2022 | |
| 48 | Michael Sims | 55 | 2003-2008 | |
| 48 | Arturo Zambrano | 55 | 2008-2013 | |
| 52 | George Draper | 54 | 2009-2013 | |
| 53 | Ramiro Herrera# | 53 | 2019-2023 | |
| 54 | Rusty Eyar | 52 | 1998-2001 | |
| 55 | Len Kirkpatrick | 51 | 1978-1982 | |
| 56 | Bruce Jackson | 50 | 1997-2003 | |
| 56 | Jesús Romero | 50 | 1999-2002 | |
| 56 | Vidal Sánchez# | 50 | 2018-2019 | |
| 56 | Luther Stout | 50 | 2006-2016 | |
| 60 | Neil Archer | 49 | 2009-2016 | |
| 60 | Benjamin Dyer | 49 | 1998-2007 | |
| 60 | Francisco Gálvez | 49 | 2004-2009 | |
| 60 | Ken Graves | 49 | 1970-1978 | |
| 60 | Juan Hernández | 49 | 2002-2013 | |
| 60 | Manuel Márquez | 49 | 2016-2019 | |
| 60 | José Morín | 49 | 1983-1993 | |
| 60 | Dave Murphy# | 49 | 2016-2019 | |
| 60 | Tony Orozco | 49 | 2001-2007 | |
| 60 | Jorge Vázquez | 49 | 1994-2003 | |
| 60 | Alex White | 49 | 1995-2000 | |
| 60 | António Yánez | 49 | 1996-2001 | |
| 72 | Ángel Durán | 48 | 2002-2011 | |
| 72 | Jim Henry | 48 | 1979-1983 | |
| 72 | Dan Hopewell | 48 | 2005-2006 | |
| 72 | Dale Kerr | 48 | 2018-2019 | |
| 72 | Jesús Mendoza | 48 | 2012-2017 | |
| 72 | Dirk Morton# | 48 | 2018-2022 | |
| 78 | Carlos Corona | 47 | 1996-2004 | |
| 78 | Héctor López | 47 | 2000-2003 | |
| 78 | Jack McNeill | 47 | 1999-2005 | |
| 78 | Scott Simpson | 47 | 1996-2000 | |
| 82 | Frank Bryan | 46 | 2003-2006 | |
| 82 | Rafael Cruz# | 46 | 2019-2022 | |
| 82 | Tim Powell | 46 | 2001-2008 | |
| 82 | Devin Sasser | 46 | 2003-2008 | |
| 86 | Félix Aguirre | 45 | 2015-2021 | |
| 86 | Salvador Fríaz | 45 | 2011-2014 | |
| 86 | Dave Hartley# | 45 | 2018-2019 | |
| 86 | Claudio Jiménez | 45 | 1995-2004 | |
| 86 | Gabriel López | 45 | 1994-1997 | |
| 86 | Wilson López | 45 | 2015-2016 | |
| 86 | Sixto Rodríguez | 45 | 2000-2004 | |
| 86 | Cody Russell | 45 | 1994-1995 | |
| 86 | Ross Stephens | 45 | 2001-2009 | |
| 86 | Jeremy Weber | 45 | 1999-2002 | |
| 96 | José Antonio Cardenas | 44 | 1998-2004 | |
| 96 | Cecil Carlson | 44 | 2001-2007 | |
| 96 | Jason Cherry | 44 | 2004-2005 | |
| 96 | Joe Cox | 44 | 2005-2009 | |
| 96 | Beau Hill# | 44 | 2016-2017 |
