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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Colton Goodwin | 86 | 2000-2005 | |
| 2 | Morgan Robinson | 81 | 2003-2004 | |
| 3 | Manuel Márquez | 79 | 2014-2019 | |
| 4 | Jaime Cruz | 78 | 1996-2001 | |
| 5 | Ta-heng Wang | 69 | 2012-2018 | |
| 6 | Pedro Castillo# | 67 | 2021-2022 | |
| 6 | Edward Deal | 67 | 1997-2003 | |
| 6 | Wayne Richards | 67 | 2004-2009 | |
| 9 | Andy Frazier | 64 | 2007-2009 | |
| 10 | Francisco Granados | 63 | 1998-2001 | |
| 11 | Ramiro Cruz | 62 | 1996-2002 | |
| 12 | José Francisco | 61 | 2008-2014 | |
| 12 | Andrés Jiménez | 61 | 2002-2008 | |
| 14 | Salvador García | 60 | 2015-2017 | |
| 14 | Randy Gladue# | 60 | 2017-2021 | |
| 14 | Jaime Nieves | 60 | 2001-2010 | |
| 17 | Al Meyer | 59 | 2000-2004 | |
| 17 | Javier Zavala | 59 | 2000-2004 | |
| 19 | Carlos Rosales | 58 | 2016-2021 | |
| 19 | Terry Snyder | 58 | 1997-2002 | |
| 21 | Jorge De La Cruz | 57 | 2010-2011 | |
| 22 | Ryan Olson | 56 | 2001-2008 | |
| 23 | Salvador Guzmán | 55 | 1995-1997 | |
| 24 | Jesús Galindo | 54 | 2009-2012 | |
| 25 | Otis Ash | 53 | 1983-1984 | |
| 25 | Júlio Contreras | 53 | 1972-1980 | |
| 25 | Joe Taylor# | 53 | 2016-2019 | |
| 28 | Rob Hallock | 52 | 2012-2015 | |
| 28 | José López | 52 | 2007-2012 | |
| 28 | Jorge Salines | 52 | 2010-2015 | |
| 31 | Davis Marsh | 51 | 2016-2019 | |
| 31 | Ray Short | 51 | 2007-2014 | |
| 31 | Jake Turner | 51 | 2009-2014 | |
| 31 | Joe Wolfe | 51 | 2001-2005 | |
| 35 | Bill Burns# | 50 | 2014-2015 | |
| 35 | César Corona | 50 | 2001-2008 | |
| 35 | Juan Díaz | 50 | 2002-2003 | |
| 35 | Steve Hall# | 50 | 2016-2017 | |
| 35 | Elwood Shepherd | 50 | 1996-2001 | |
| 35 | Joshua Simpson | 50 | 2002-2010 | |
| 35 | Ronald Sims | 50 | 1998-2007 | |
| 35 | Jeremy Wood | 50 | 2008-2013 | |
| 43 | Mike Atkinson | 49 | 1999-2006 | |
| 43 | Christian Johnston | 49 | 1970-1976 | |
| 43 | Kichisaburo Sato | 49 | 2016-2018 | |
| 43 | Michael Sparks | 49 | 2003-2014 | |
| 47 | Tommy Beasley | 48 | 1999-2003 | |
| 47 | Ken Bennett | 48 | 2008-2010 | |
| 47 | Mario Blanco# | 48 | 2017-2018 | |
| 47 | Tom Day | 48 | 2014-2016 | |
| 47 | Omar Encarnación | 48 | 2000-2004 | |
| 47 | Ramiro Herrera# | 48 | 2018-2019 | |
| 47 | Matt Hughes# | 48 | 2015-2016 | |
| 47 | Anthony Leary | 48 | 2001-2010 | |
| 47 | Emory Sanders | 48 | 1999-2003 | |
| 47 | Theron Simon | 48 | 2002-2009 | |
| 57 | Miguel Castaneda | 47 | 2014-2020 | |
| 57 | George Doss | 47 | 1998-1999 | |
| 57 | Blake Foster# | 47 | 2015-2017 | |
| 57 | Zack Marsh | 47 | 2005-2008 | |
| 57 | Kurt O'Neil | 47 | 1981-1982 | |
| 57 | Joseph Stewart | 47 | 2002-2004 | |
| 63 | Héctor Aguilar | 46 | 2016-2021 | |
| 63 | Jason Curry | 46 | 2004-2005 | |
| 63 | José Martínez | 46 | 1996-2004 | |
| 63 | Willie Myers | 46 | 2002-2009 | |
| 63 | Gilberto Tapia | 46 | 2007-2009 | |
| 68 | Andy Edwards | 45 | 2013-2018 | |
| 68 | Anastasio González | 45 | 2000-2001 | |
| 68 | Jorge Herrera | 45 | 2016-2018 | |
| 68 | Norm Joyce | 45 | 2000-2003 | |
| 68 | John Massey | 45 | 2012-2015 | |
| 68 | Tony Thomas | 45 | 2009-2015 | |
| 68 | Brian Tucker | 45 | 2012-2015 | |
| 68 | Rafael Vega | 45 | 2014-2016 | |
| 76 | Joe Collins | 44 | 1995-1997 | |
| 76 | Gordon Faulkner | 44 | 1998-2004 | |
| 76 | Christopher Inches# | 44 | 2019-2022 | |
| 76 | Ramón Moya | 44 | 2005-2007 | |
| 76 | Francisco Reyes | 44 | 2002-2009 | |
| 76 | Miguel Angel Rodríguez | 44 | 1998-2001 | |
| 76 | Vance Smith | 44 | 2000-2002 | |
| 83 | Jason Cherry | 43 | 2004-2004 | |
| 83 | William Graves | 43 | 2002-2004 | |
| 83 | John Hawkins# | 43 | 2014-2014 | |
| 83 | Juan Montés# | 43 | 2016-2023 | |
| 83 | Ángel Valdés | 43 | 1997-2003 | |
| 88 | Tony Durdle | 42 | 1980-1985 | |
| 88 | Stephen Forrest | 42 | 2006-2014 | |
| 88 | Joe Galloway | 42 | 2012-2014 | |
| 88 | Cipriano Germán | 42 | 2009-2013 | |
| 88 | Ray King | 42 | 1995-2000 | |
| 88 | Chris Lee# | 42 | 2015-2016 | |
| 88 | Bill Moon# | 42 | 2022-2022 | |
| 88 | Dan Quick | 42 | 1995-2003 | |
| 88 | Javier Rojas | 42 | 2001-2006 | |
| 88 | Dudley Shepherd | 42 | 1975-1980 | |
| 88 | Rick Swain | 42 | 2001-2006 | |
| 88 | Héctor Vera | 42 | 2012-2016 | |
| 88 | Steve Watts# | 42 | 2017-2019 |
