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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Juan Casas | 85 | 2003-2005 | |
| 1 | Ray Richard | 85 | 2003-2005 | |
| 3 | Germán Hernández | 80 | 2009-2013 | |
| 4 | Mark Jackson | 66 | 2003-2005 | |
| 4 | Jeffery McCarthy | 66 | 2009-2013 | |
| 6 | Fred Holloway | 63 | 2009-2014 | |
| 7 | Richard Teutsch# | 58 | 2019-2021 | |
| 8 | Chris Ellis | 56 | 2009-2011 | |
| 9 | Pablo Torres | 54 | 2000-2015 | |
| 10 | Andrew Kirkland | 53 | 1996-1999 | |
| 11 | Tim Adams | 52 | 1999-2003 | |
| 12 | Claudio Estrada | 51 | 2004-2006 | |
| 12 | Richard McElroy# | 51 | 2016-2018 | |
| 14 | José Chávez# | 50 | 2019-2021 | |
| 14 | Bob Dorsey# | 50 | 2017-2018 | |
| 16 | Michael Miller | 48 | 2001-2002 | |
| 16 | José Rositas# | 48 | 2017-2019 | |
| 18 | Todd Merritt | 47 | 2007-2009 | |
| 19 | Doug Stokes | 46 | 1998-1999 | |
| 19 | Keith Traill | 46 | 2000-2004 | |
| 21 | Bennie Mueller | 45 | 2002-2003 | |
| 21 | Jorge Sandoval# | 45 | 2021-2023 | |
| 21 | Joel Shaffer | 45 | 1982-1988 | |
| 21 | Francis Taylor | 45 | 2014-2017 | |
| 21 | Juan Vásquez | 45 | 1974-1979 | |
| 26 | José Ramos | 44 | 2002-2004 | |
| 26 | Cory Walter# | 44 | 2013-2014 | |
| 28 | Harry Bannatyne | 43 | 2001-2002 | |
| 28 | Jeffrey Cook | 43 | 2004-2007 | |
| 28 | Don Drake | 43 | 2012-2014 | |
| 28 | António Garza | 43 | 2000-2003 | |
| 28 | Leland Hunt# | 43 | 2021-2022 | |
| 28 | Darwin Parks | 43 | 2003-2004 | |
| 28 | Lorenzo Rivera# | 43 | 2021-2022 | |
| 28 | Hiroyasu Watanabe | 43 | 2013-2015 | |
| 36 | Emerson Anderson | 42 | 2000-2002 | |
| 36 | Juan Armiso# | 42 | 2019-2021 | |
| 36 | Jim Galloway# | 42 | 2016-2017 | |
| 36 | Edgardo Guillén | 42 | 2012-2014 | |
| 36 | Ron MacNamara# | 42 | 2020-2021 | |
| 41 | Cory Hayes# | 41 | 2017-2020 | |
| 41 | Tyler Knight# | 41 | 2017-2021 | |
| 41 | José Núńez# | 41 | 2017-2017 | |
| 41 | Scott Perales | 41 | 2015-2018 | |
| 41 | Jake Riley# | 41 | 2015-2017 | |
| 41 | Vidal Sánchez# | 41 | 2017-2017 | |
| 47 | Jorge De La Cruz | 40 | 2009-2009 | |
| 47 | Ron Johnson | 40 | 2002-2004 | |
| 47 | Pancho Ortíz | 40 | 2013-2021 | |
| 47 | Sean Roberts | 40 | 2010-2015 | |
| 47 | Martin Williams | 40 | 1997-2006 | |
| 47 | António Yan | 40 | 2011-2011 | |
| 53 | Martín Baraja# | 39 | 2021-2023 | |
| 53 | Mike Field# | 39 | 2021-2023 | |
| 53 | Bob Hahn | 39 | 2002-2005 | |
| 53 | Kevin Hatch | 39 | 2002-2003 | |
| 53 | Bob King | 39 | 2009-2013 | |
| 53 | Davis Marsh | 39 | 2015-2015 | |
| 53 | Cisco Mendoza | 39 | 2002-2002 | |
| 53 | Rod Mitchell | 39 | 2003-2009 | |
| 53 | Duane Reed# | 39 | 2021-2022 | |
| 53 | Don Winters# | 39 | 2021-2021 | |
| 63 | Doug Blackburn | 38 | 1982-1986 | |
| 63 | Dan Booker | 38 | 2013-2018 | |
| 63 | Bill Grant | 38 | 2002-2004 | |
| 63 | Pete Jackson# | 38 | 2019-2020 | |
| 63 | Bastian Jordan | 38 | 1992-1997 | |
| 63 | Cipriano Morales# | 38 | 2020-2020 | |
| 63 | Bill Winston# | 38 | 2020-2021 | |
| 70 | José Gonzáles | 37 | 2001-2005 | |
| 70 | Greg Harvey# | 37 | 2018-2019 | |
| 70 | Nesto Rivera# | 37 | 2021-2023 | |
| 70 | Félix Román | 37 | 2009-2015 | |
| 70 | León Sánchez# | 37 | 2016-2016 | |
| 70 | Terry Smith | 37 | 2013-2014 | |
| 70 | César Trejo | 37 | 2003-2004 | |
| 70 | Mark Williams | 37 | 1997-2005 | |
| 78 | Manuel Cruz | 36 | 2009-2015 | |
| 78 | Fernando Flores | 36 | 2000-2006 | |
| 78 | Stan Newman# | 36 | 2016-2017 | |
| 78 | Carlos Quintana# | 36 | 2018-2021 | |
| 78 | Andy Wilcox# | 36 | 2020-2021 | |
| 83 | Santiago Barrón | 35 | 2009-2016 | |
| 83 | Ben Carter# | 35 | 2022-2022 | |
| 83 | Frank Davis | 35 | 2000-2001 | |
| 83 | Harley Elliott# | 35 | 0-0 | |
| 83 | Ramón Hernández# | 35 | 2022-2022 | |
| 83 | Miguel Molina | 35 | 2002-2003 | |
| 83 | Felipe Negrón# | 35 | 2017-2017 | |
| 83 | Jeff Richardson# | 35 | 2016-2017 | |
| 83 | Dave Ross | 35 | 2001-2002 | |
| 83 | Pepe Santos | 35 | 1996-2000 | |
| 83 | Vincent Watson | 35 | 1997-1999 | |
| 83 | Adam Williams# | 35 | 2018-2021 | |
| 95 | Quinn Cannon | 34 | 0-0 | |
| 95 | Jerry Carter# | 34 | 2021-2021 | |
| 95 | Rafael Chávez | 34 | 2002-2005 | |
| 95 | Curt Creasy | 34 | 2003-2006 | |
| 95 | Steve Hughes# | 34 | 2018-2020 | |
| 95 | Carlos Jiménez | 34 | 1999-2004 |
