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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Dave Moore | 1.364 | 1975 | |
| 2 | Lucas Park | 1.548 | 1992 | |
| 3 | Noel McGill | 1.609 | 2013 | |
| 4 | Gavin Wright# | 1.731 | 2017 | |
| 5 | Álex Valentín | 1.750 | 1994 | |
| 6 | Jorge Berrios# | 1.762 | 2017 | |
| 7 | Carl Padgett | 1.804 | 1975 | |
| 8 | Lorenzo Pérez | 1.821 | 1973 | |
| 9 | Rich Hodge# | 1.831 | 2017 | |
| 10 | Iemitsu Hasegawa | 1.856 | 1992 | |
| 11 | Jesús Morales | 1.935 | 1996 | |
| 12 | Bernardo Gómez | 2.005 | 1993 | |
| 12 | Tony Ford | 2.005 | 1975 | |
| 14 | Dale Jones | 2.009 | 1996 | |
| 15 | Felipe Alsina | 2.017 | 1992 | |
| 16 | Brant Kennedy | 2.019 | 1992 | |
| 17 | Eddie Ferrell | 2.048 | 1995 | |
| 18 | Felipe Juárez | 2.050 | 1978 | |
| 19 | Mike Funk | 2.052 | 1975 | |
| 20 | Bob Bennion | 2.055 | 1982 | |
| 21 | Mike Buckley# | 2.065 | 2013 | |
| 22 | Earl Moss | 2.074 | 1978 | |
| 23 | Ron Davis | 2.081 | 1973 | |
| 24 | Kent Nixon | 2.082 | 1996 | |
| 25 | Doug Powell | 2.139 | 2016 | |
| 26 | Mike Sullivan | 2.150 | 1986 | |
| 27 | Ánibal Nieves | 2.152 | 1975 | |
| 28 | Cordell Sharp | 2.180 | 1992 | |
| 29 | Wayne Lee | 2.190 | 2010 | |
| 30 | Jason Carson | 2.200 | 1992 | |
| 31 | Pepe Muńóz | 2.208 | 1973 | |
| 31 | Bruce Perry | 2.208 | 1992 | |
| 33 | Ron Hannah | 2.213 | 1984 | |
| 33 | A.R. Sears | 2.213 | 1992 | |
| 35 | Diego Padilla | 2.221 | 1994 | |
| 36 | José Ortíz | 2.236 | 1979 | |
| 37 | Jorge Vega | 2.247 | 1992 | |
| 38 | Martín Durán | 2.277 | 2006 | |
| 39 | Chad Cooper | 2.309 | 2012 | |
| 40 | Chris Curry | 2.321 | 1996 | |
| 41 | Lee Webb | 2.327 | 1979 | |
| 42 | Vicente Mata | 2.353 | 1994 | |
| 43 | Marvin Richardson | 2.368 | 1985 | |
| 44 | Timothy Baker | 2.382 | 1983 | |
| 45 | Guillermo Herrera | 2.387 | 1973 | |
| 46 | Gene Wilson | 2.403 | 1976 | |
| 47 | Carl Padgett | 2.417 | 1976 | |
| 48 | Marty James | 2.419 | 1974 | |
| 48 | Todd King | 2.419 | 2012 | |
| 50 | Richard Johnston | 2.426 | 1973 | |
| 51 | Juan Iturbide | 2.433 | 1996 | |
| 51 | Rex Dudley# | 2.433 | 2017 | |
| 53 | José Farías | 2.438 | 2008 | |
| 54 | Stanley Stone | 2.455 | 1995 | |
| 55 | John O'Donnell | 2.475 | 2010 | |
| 55 | Vincent Joyce# | 2.475 | 2017 | |
| 57 | Alan Wilson# | 2.482 | 2017 | |
| 58 | Buddy Clark# | 2.484 | 2017 | |
| 59 | Carson Whittier | 2.486 | 1981 | |
| 59 | Stephen Dannatt | 2.486 | 1995 | |
| 61 | Vicente Gonzáles | 2.488 | 2008 | |
| 62 | Jacob Rowe | 2.501 | 1974 | |
| 63 | León Estrada | 2.507 | 2013 | |
| 63 | Andy Huckaby | 2.507 | 2007 | |
| 65 | Rafael Ceprda# | 2.512 | 2014 | |
| 66 | Royce Goodwin | 2.519 | 1987 | |
| 66 | Matt Pitts | 2.519 | 2013 | |
| 68 | Riley Crawfurd | 2.521 | 1973 | |
| 69 | Stephen Workman | 2.530 | 2017 | |
| 70 | Iván Cardenas# | 2.534 | 2014 | |
| 71 | José Martínez# | 2.539 | 2012 | |
| 72 | Dave Copeland | 2.543 | 1993 | |
| 73 | Chris Russell | 2.551 | 2007 | |
| 73 | Roberto Moreno | 2.551 | 1994 | |
| 75 | Edward Daniels | 2.552 | 1992 | |
| 76 | Kuniaki Maeda | 2.553 | 2007 | |
| 77 | Carl Padgett | 2.561 | 1973 | |
| 78 | Eduardo Heredia | 2.562 | 1996 | |
| 79 | Ron Dixon | 2.564 | 1983 | |
| 80 | Michael Young | 2.567 | 1997 | |
| 81 | Scott Borst | 2.573 | 1993 | |
| 81 | Don Lambert | 2.573 | 1983 | |
| 83 | Brian Stevens# | 2.587 | 2022 | |
| 84 | António Castro# | 2.589 | 2017 | |
| 85 | Gerardo Uribe | 2.596 | 1983 | |
| 86 | Ed Collins | 2.607 | 1997 | |
| 87 | Han Xú | 2.608 | 1992 | |
| 88 | Blake Watts# | 2.617 | 2014 | |
| 89 | Tim Sharpe | 2.629 | 1975 | |
| 90 | Kazuhiko Kichida | 2.638 | 1994 | |
| 91 | Flynn Davis | 2.646 | 2017 | |
| 92 | Paul Pierce | 2.649 | 2013 | |
| 93 | Domingo Madrigal | 2.650 | 1976 | |
| 94 | Leon González | 2.651 | 1986 | |
| 95 | Raymond Nelson | 2.657 | 1973 | |
| 96 | Ramón Díaz | 2.671 | 1982 | |
| 97 | Tom Taylor | 2.676 | 1986 | |
| 98 | Marty Branch | 2.684 | 1994 | |
| 99 | Matt Bergeron | 2.696 | 1978 | |
| 100 | Jesús Hernández | 2.700 | 1996 |
