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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | José García | 1.022 | 1974 | |
| 2 | Jim Steele | 1.257 | 1982 | |
| 3 | Phil Cooper | 1.426 | 1994 | |
| 4 | King George | 1.481 | 1997 | |
| 5 | Román Beltrán | 1.542 | 1992 | |
| 6 | Paul Brooks | 1.608 | 1992 | |
| 7 | Armando Betancourt | 1.628 | 1995 | |
| 8 | John Murphy# | 1.654 | 2016 | |
| 9 | Dewey Martin | 1.708 | 1992 | |
| 10 | Oliver LeBlanc | 1.714 | 1994 | |
| 11 | Alex Shannon | 1.719 | 1993 | |
| 12 | Arturo Cruz | 1.751 | 1972 | |
| 13 | Jack Shaw | 1.762 | 1979 | |
| 14 | Jeff MacDonald | 1.772 | 1985 | |
| 15 | Alonso Castillo | 1.789 | 1992 | |
| 16 | Stu Smith | 1.793 | 1972 | |
| 17 | Alejandro Fernández | 1.890 | 1992 | |
| 18 | Cory Gregory | 1.896 | 1994 | |
| 19 | Ramón Carrasco | 1.898 | 1972 | |
| 20 | Pepe Hernández | 1.907 | 1976 | |
| 21 | Robert Ray | 1.922 | 1973 | |
| 22 | José Silva | 1.962 | 1982 | |
| 23 | Manny Cruz | 1.965 | 1992 | |
| 24 | Jonathon Bishop | 1.983 | 1994 | |
| 25 | Juan Martínez | 1.988 | 1989 | |
| 26 | Clement Stevens | 1.990 | 1988 | |
| 27 | Armando Huerta | 1.997 | 1972 | |
| 28 | Gene Fox | 2.002 | 1987 | |
| 29 | Octávio Ayala | 2.005 | 1981 | |
| 30 | Jeff DeWalt | 2.010 | 1982 | |
| 31 | Dan Wheeler | 2.013 | 1976 | |
| 32 | Glen White | 2.038 | 2014 | |
| 33 | Matt Sexton | 2.051 | 1972 | |
| 34 | Mike Little | 2.054 | 1997 | |
| 35 | Jimmy Roberts | 2.069 | 2014 | |
| 36 | Michael Simmons | 2.071 | 1994 | |
| 37 | Ray Jones | 2.073 | 1977 | |
| 37 | James Brennan | 2.073 | 1972 | |
| 39 | Eddie Acosta | 2.102 | 1995 | |
| 39 | Sergio Mercado | 2.102 | 1979 | |
| 41 | Jaime Juárez | 2.112 | 1992 | |
| 42 | Scott Faulkner | 2.122 | 1987 | |
| 43 | Rudy Chávez | 2.143 | 1997 | |
| 44 | Jeff Lynch | 2.144 | 2013 | |
| 45 | Tony Blake | 2.156 | 1994 | |
| 46 | Reese Maxwell | 2.158 | 1992 | |
| 47 | Jon Brewer | 2.166 | 1978 | |
| 48 | Mark Cates | 2.167 | 1980 | |
| 49 | Kevin Wiggins | 2.172 | 1977 | |
| 50 | Bob Baker | 2.175 | 1992 | |
| 50 | Justin Harris | 2.175 | 1994 | |
| 52 | Felipe Pineda | 2.198 | 1977 | |
| 53 | Scott Cooper | 2.200 | 1979 | |
| 54 | Johnny Merritt | 2.206 | 1995 | |
| 54 | Greg Hunt | 2.206 | 2007 | |
| 56 | Jared Spitz | 2.218 | 1993 | |
| 57 | Mauro Moreno | 2.226 | 1992 | |
| 58 | Brian Rath | 2.232 | 1979 | |
| 59 | Scott Laws | 2.236 | 1983 | |
| 60 | Hee-seop Pak | 2.241 | 1981 | |
| 61 | Frank Worth | 2.259 | 1983 | |
| 62 | Tony De La Teja | 2.268 | 1980 | |
| 63 | Félix Gutiérrez | 2.281 | 1987 | |
| 64 | Tom Campbell* | 2.307 | 1975 | |
| 65 | José Mejía | 2.323 | 1978 | |
| 66 | Bob Oliver | 2.330 | 1973 | |
| 67 | Chuck Shinamius | 2.336 | 2006 | |
| 68 | Jorge Cruz | 2.346 | 1975 | |
| 69 | Jeff Farris | 2.355 | 1992 | |
| 70 | Héctor Delgado | 2.364 | 1973 | |
| 71 | Rob Martin | 2.372 | 2011 | |
| 71 | Pepe Pregaso | 2.372 | 1984 | |
| 73 | Drew Brown | 2.380 | 1983 | |
| 74 | Francisco Martínez | 2.392 | 1973 | |
| 75 | Félix Bonilla | 2.394 | 1973 | |
| 75 | Ken Hunt | 2.394 | 1979 | |
| 77 | Tony Parker | 2.401 | 1978 | |
| 78 | Peyton Meyer | 2.405 | 2013 | |
| 79 | Brian Kline | 2.407 | 1978 | |
| 80 | José Garza | 2.411 | 1973 | |
| 81 | Orlando Pérez | 2.418 | 1977 | |
| 82 | James Davis | 2.419 | 1994 | |
| 83 | Nathan Thompson | 2.424 | 1998 | |
| 84 | Jeff Tapping | 2.430 | 2014 | |
| 84 | Juan Vásquez | 2.430 | 1981 | |
| 86 | Howard Stone | 2.431 | 1979 | |
| 86 | Bailey Albertson | 2.431 | 1981 | |
| 88 | Laurente Ciappara | 2.439 | 1982 | |
| 89 | Keith Robinson | 2.442 | 1996 | |
| 89 | Julian Gregory | 2.442 | 1974 | |
| 91 | Curt Bullard | 2.447 | 1993 | |
| 92 | Todd Brown | 2.451 | 2013 | |
| 92 | Jason Avery | 2.451 | 1975 | |
| 94 | Chad Thomas | 2.455 | 1977 | |
| 94 | Rob Smith | 2.455 | 2007 | |
| 94 | Bob Boyle | 2.455 | 1989 | |
| 94 | Theodore Hall | 2.455 | 2016 | |
| 98 | Richard Hall | 2.461 | 2014 | |
| 99 | Philip Higgins | 2.463 | 2017 | |
| 100 | Stephen Perkins | 2.465 | 1983 |
