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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Terry Hansen | 72 | 2005-2007 | |
| 2 | Jesús Alonzo | 69 | 2000-2004 | |
| 3 | Bill Lewis | 66 | 2001-2002 | |
| 4 | Esteban Polanco | 65 | 2004-2006 | |
| 5 | Andrés Jiménez | 62 | 2000-2003 | |
| 5 | Brad Kennedy | 62 | 2000-2009 | |
| 7 | Oscar McCarthy# | 59 | 2018-2021 | |
| 7 | Andrew McDonald | 59 | 2000-2002 | |
| 9 | Andy Murphy | 55 | 2001-2003 | |
| 9 | Edward Pope | 55 | 2004-2005 | |
| 9 | Michael Woodard | 55 | 2008-2009 | |
| 12 | Randy Gross# | 54 | 2017-2018 | |
| 13 | Steve Collins# | 53 | 2017-2018 | |
| 13 | Ángel Cuevas# | 53 | 2019-2020 | |
| 13 | José Mendoza | 53 | 2014-2021 | |
| 13 | Rocky Mitchell# | 53 | 2021-2021 | |
| 13 | Alex Ward# | 53 | 2018-2019 | |
| 13 | Kevin Wolfe | 53 | 2000-2006 | |
| 19 | Tim Small | 52 | 1996-2001 | |
| 20 | Mauro Franco | 51 | 2000-2003 | |
| 20 | Jesús Galindo | 51 | 2008-2008 | |
| 22 | Marvin Bush | 50 | 2002-2006 | |
| 22 | Glen McMartin | 50 | 2000-2002 | |
| 24 | George Brewer# | 49 | 2019-2019 | |
| 24 | George Brown | 49 | 2000-2001 | |
| 24 | Jack Fullerton# | 49 | 2016-2018 | |
| 27 | Luis Ortega# | 48 | 2016-2016 | |
| 27 | Vaughn Thomas# | 48 | 2016-2017 | |
| 29 | Ed Vaughn | 47 | 2001-2003 | |
| 30 | Glenn Carpenter | 46 | 2001-2009 | |
| 30 | Roberto Cortéz | 46 | 2001-2002 | |
| 32 | Artie Conway | 45 | 2001-2002 | |
| 32 | Sam Noble | 45 | 1999-2001 | |
| 32 | Luis Quiñones# | 45 | 2019-2020 | |
| 32 | Richard Taylor | 45 | 2003-2003 | |
| 36 | Michael Harper# | 44 | 2018-2020 | |
| 36 | Riley King | 44 | 2010-2012 | |
| 36 | José López | 44 | 2005-2007 | |
| 36 | Scott McSweeny | 44 | 2009-2010 | |
| 36 | José Mejía# | 44 | 2018-2020 | |
| 41 | Kevin Gilbert | 43 | 1997-1999 | |
| 41 | Martin Sterling | 43 | 1999-2001 | |
| 41 | Dave Timothy | 43 | 2014-2017 | |
| 44 | Ken Austin | 42 | 1999-2001 | |
| 44 | Del Becker | 42 | 2000-2000 | |
| 44 | Stéphane Faubert | 42 | 2009-2009 | |
| 44 | Rafael Fernández | 42 | 2014-2016 | |
| 44 | Javier Martínez | 42 | 2005-2010 | |
| 44 | Marcos Quezada | 42 | 2001-2009 | |
| 44 | Ron Watson | 42 | 2008-2011 | |
| 51 | César Corona | 41 | 2001-2006 | |
| 51 | Dave MacIntyre | 41 | 2004-2004 | |
| 51 | Travis Owens# | 41 | 2016-2018 | |
| 51 | Matthew Rodgers# | 41 | 2011-2012 | |
| 51 | Clarence Sheppard# | 41 | 2020-2021 | |
| 56 | Lonnie Lambert | 40 | 2001-2003 | |
| 56 | Richard Morrison | 40 | 2003-2011 | |
| 56 | António Negrete | 40 | 2000-2004 | |
| 56 | Brock Weber# | 40 | 2022-2023 | |
| 56 | Leon White | 40 | 2010-2010 | |
| 61 | Pat Crouch# | 39 | 2018-2019 | |
| 61 | Clancy Gaston# | 39 | 2017-2019 | |
| 61 | Micah Howard | 39 | 2001-2002 | |
| 61 | Greg Howell | 39 | 2002-2004 | |
| 61 | Juan Ríos | 39 | 2014-2017 | |
| 61 | Mark Williams | 39 | 1997-1999 | |
| 67 | Craig Cooper | 38 | 2006-2014 | |
| 67 | George Hughes | 38 | 1978-1982 | |
| 67 | Jack Richardson | 38 | 2002-2003 | |
| 67 | Mike Thomas | 38 | 2001-2002 | |
| 71 | Mike Beggs | 37 | 1997-2003 | |
| 71 | Nathan Hayden | 37 | 1996-2000 | |
| 71 | Manuel Martínez | 37 | 2004-2005 | |
| 74 | Ed Arthur | 36 | 2003-2003 | |
| 74 | Tony Cruz | 36 | 2009-2010 | |
| 74 | Mark Floyd# | 36 | 2015-2016 | |
| 74 | Dusty Hardy | 36 | 2003-2004 | |
| 74 | Mike Moss | 36 | 1990-2004 | |
| 74 | Robinson Reyes | 36 | 2010-2011 | |
| 74 | Paul Tschiffely | 36 | 1997-2002 | |
| 74 | Wes Williams# | 36 | 2017-2018 | |
| 82 | Floyd Anderson | 35 | 2008-2008 | |
| 82 | Stephen Bailey# | 35 | 2015-2018 | |
| 82 | Bob Brown | 35 | 2001-2004 | |
| 82 | Roy Buckner# | 35 | 2015-2019 | |
| 82 | Jason Curry | 35 | 2002-2003 | |
| 82 | Chris Davis# | 35 | 2018-2021 | |
| 82 | Juan Gomález | 35 | 2002-2004 | |
| 82 | Robert Houston | 35 | 2000-2001 | |
| 82 | Júlio Peralta# | 35 | 2020-2020 | |
| 91 | José Ángel | 34 | 2014-2021 | |
| 91 | Alfredo Arévalo# | 34 | 2018-2019 | |
| 91 | Anderson Augustus | 34 | 2008-2009 | |
| 91 | Sergio Domínguez | 34 | 2013-2017 | |
| 91 | Carlos Flores# | 34 | 2017-2018 | |
| 91 | Jean-Philippe Gauvreau# | 34 | 2015-2017 | |
| 91 | Roberto Hernández | 34 | 2007-2008 | |
| 91 | Ronaldo Hernández | 34 | 1999-2005 | |
| 91 | Michael MacIntosh | 34 | 2005-2008 | |
| 91 | Jaime Nieves | 34 | 2000-2001 |
