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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Don Kelly* | 515 | 1984-2001 | |
| 2 | Stéfano López* | 410 | 1975-1990 | |
| 3 | Raúl Rodríguez | 372 | 2008-2021 | |
| 4 | Germán Ortíz | 370 | 1983-1998 | |
| 5 | Dustin Hawkins* | 365 | 2003-2018 | |
| 6 | Tim Myers | 357 | 1970-1987 | |
| 7 | Mario Mercado | 346 | 2008-2021 | |
| 8 | Mike Smith | 302 | 1981-1995 | |
| 9 | Jim Huffman | 292 | 1995-2013 | |
| 10 | Ramón Morán | 283 | 2002-2016 | |
| 11 | Joe Givens | 278 | 1994-2006 | |
| 12 | Kenny Dukes | 267 | 2006-2022 | |
| 13 | Lorenzo Mejía | 262 | 1998-2014 | |
| 14 | Emílio Cabrera | 238 | 1979-1993 | |
| 15 | Frederick Mitchell# | 232 | 2011-2023 | |
| 16 | Stephen Caldwell | 220 | 1978-1993 | |
| 17 | Jesús Reyes | 217 | 1986-2000 | |
| 18 | Albert Pérez | 209 | 1993-2005 | |
| 19 | Sam Leonard | 208 | 2002-2014 | |
| 20 | Miguel Sánchez# | 195 | 2010-2023 | |
| 21 | Joe Hamilton | 194 | 2001-2018 | |
| 22 | Pedro Sandoval | 183 | 2001-2018 | |
| 23 | John Black# | 180 | 2013-2023 | |
| 24 | Austin Horton | 175 | 2002-2014 | |
| 25 | Ryan Pope# | 174 | 2008-2023 | |
| 26 | Rafael Pérez# | 172 | 2005-2023 | |
| 27 | Billy Miller | 164 | 1997-2013 | |
| 28 | David Arévalo | 163 | 1970-1982 | |
| 28 | Robert Belcher | 163 | 2008-2018 | |
| 30 | Martín Martínez | 162 | 2003-2016 | |
| 31 | Carlos Pérez | 161 | 1986-2000 | |
| 32 | Lance Pryor | 160 | 1970-1979 | |
| 33 | Quinn Gilsthorpe | 157 | 1984-1991 | |
| 34 | Jorge Martínez# | 156 | 2016-2023 | |
| 35 | Henry Winman | 155 | 1986-1999 | |
| 36 | Woody Allen | 153 | 2000-2008 | |
| 36 | Joe Warren* | 153 | 1983-1996 | |
| 38 | Will Williams | 150 | 1994-2005 | |
| 39 | Manol Travassos# | 149 | 2014-2023 | |
| 40 | Jim Jones# | 143 | 2016-2023 | |
| 40 | Chris Murphy | 143 | 2001-2010 | |
| 42 | Peter Cochran | 142 | 2011-2017 | |
| 42 | Ernesto Gómez | 142 | 2012-2021 | |
| 42 | Jack Meyer | 142 | 1970-1983 | |
| 45 | Karl Reed | 138 | 1975-1985 | |
| 46 | Mark Jackson | 137 | 1988-2002 | |
| 46 | Jorge Rea# | 137 | 2014-2023 | |
| 48 | Pablo Guillén | 136 | 1983-1997 | |
| 49 | Luis Gómes | 135 | 1995-2004 | |
| 50 | Michael Jenkins | 131 | 1983-1993 | |
| 50 | Donald Kelly | 131 | 2001-2010 | |
| 50 | David Kimble | 131 | 1974-1992 | |
| 50 | Ricardo Manuel | 131 | 1978-1992 | |
| 54 | Vincente Báez | 127 | 1977-1990 | |
| 54 | Robert Cobb | 127 | 2009-2020 | |
| 56 | Júlio Román | 126 | 1986-1996 | |
| 57 | Logan Ritter | 121 | 1980-1989 | |
| 58 | Rintaro Oyama | 120 | 1995-2003 | |
| 59 | Gilberto Muńóz | 118 | 2009-2022 | |
| 60 | David Cortés | 117 | 2002-2016 | |
| 60 | Esteban Rodríguez | 117 | 2008-2019 | |
| 62 | Jeffery Becker | 116 | 1996-2008 | |
| 62 | Boyd Bleeker | 116 | 1977-1988 | |
| 62 | Ramón Muńóz | 116 | 1997-2003 | |
| 65 | Donald Dusek | 115 | 1998-2007 | |
| 66 | Edward McNeil | 113 | 1970-1981 | |
| 67 | Craig Maynard | 112 | 2004-2020 | |
| 68 | Ty Kelly | 109 | 2003-2011 | |
| 69 | Jonathan Manning | 108 | 2002-2017 | |
| 69 | Tex Robinson | 108 | 1989-1996 | |
| 71 | Eric Booth | 106 | 1985-1998 | |
| 71 | Scott Funk | 106 | 2005-2017 | |
| 71 | Félix Mateo | 106 | 1987-1994 | |
| 74 | John Parker | 105 | 1976-1985 | |
| 74 | Ángel Rosa | 105 | 1981-1983 | |
| 76 | Gabriel Silva | 104 | 1999-2012 | |
| 77 | Jason Greene | 103 | 1972-1980 | |
| 78 | Tommy Brown | 101 | 1993-2004 | |
| 79 | Eliot Arrington | 100 | 1970-1977 | |
| 79 | Gene Baker# | 100 | 2016-2023 | |
| 81 | José Gonzáles | 99 | 2012-2019 | |
| 81 | Ryo Hayashi | 99 | 1970-1976 | |
| 81 | Curt Wagner | 99 | 1970-1979 | |
| 84 | Forrest Ward# | 97 | 2011-2023 | |
| 84 | Zack Wright | 97 | 2007-2015 | |
| 86 | Brian Armstrong | 96 | 2010-2017 | |
| 86 | Juan Bravo | 96 | 2006-2014 | |
| 86 | Michael Hargrove | 96 | 2014-2021 | |
| 86 | Joe Johnson | 96 | 1997-2007 | |
| 90 | George Jones | 95 | 1970-1983 | |
| 90 | Miguel Torres | 95 | 1990-2001 | |
| 92 | Alfred Bennett | 94 | 1970-1975 | |
| 92 | Pancho Rivera | 94 | 2000-2017 | |
| 94 | Morton Clayton | 92 | 2010-2021 | |
| 94 | Juan Olivares | 92 | 1982-1992 | |
| 96 | Bob DeWalt | 91 | 1986-1993 | |
| 96 | Félix García | 91 | 1994-2002 | |
| 96 | Keith Whitfield* | 91 | 1985-2000 | |
| 99 | Victor Hicks# | 90 | 2012-2023 | |
| 99 | Paul Meyer | 90 | 2001-2011 |
